FIELD: organic chemistry, chemical technology, pharmacy. SUBSTANCE: invention relates to method for preparing 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H- imidazole-1-yl)methyl]-4H-carbazole-4-one of the formula (I) 
. Method involves interaction of tetrahydrocarbazolone of the formula (IV) 
with morpholine at temperature from 110 C to phlegm point with addition of formaldehyde or paraformaldehyde to yield compound of the formula (III) 
that is subjected then to interaction with 2-methylimidazole to yield 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazole-1-yl)methyl] -4H-carbazole-4-one of the formula (I). Invention can be used in synthesis of chemical compounds as active components in pharmacological preparations. EFFECT: enhanced economy and safety of process.
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|---|---|---|---|
| METHOD OF OBTAINING IMIDAZOLE DERIVATIVES OR THEIR PHYSIOLOGICALLY ACCEPTABLE SALTS | 0 |
|
SU1528319A3 |
| PROCESS FOR PREPARING 1,2,3,9-TETRAHYDRO -9-METHYL -3-[(2-METHYL-1H-IMIDAZOL -1-YL)METHYL]-4H- CARBAZOL-4-ONE OR SALTS THEREOF OR HYDRATES THEREOF, AND INTERMEDIATE PRODUCTS OF SYNTHESIS THEREOF | 1993 |
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