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2 423 977

(13)

(51)

IPC

A61K31/4409(2006-01-01)

A61K31/145(2006-01-01)

A61K9/00(2006-01-01)

A61K9/30(2006-01-01)

A61K9/02(2006-01-01)

A61J3/10(2006-01-01)

A61P31/06(2006-01-01)

(21) (22)

Application

2010115705/15, 2010-04-20

(24)

Start date

2010-04-20

(22)

Actual filing date

2010-04-20

(45)

Published

2011-07-20

(72)

Inventor

Gushchin Aleksandr SergeevichVinogradova Tat'Jana IvanovnaJablonskij Petr KazimirovichBatjunin Gennadij AndreevichZabolotnykh Natal'Ja VjacheslavovnaVasil'Eva Svetlana NikolaevnaMalygin Aleksej Vladimirovich

(73)

Holder

Otkrytoe Aktsionernoe Obshchestvo

ANTI-TUBERCULOSIS MEDICATION BASED ON 4-THIOUREIDOIMINOMETHYLPYRIDINIUM PERCHLORATE, METHOD OF ITS OBTAINING AND METHOD OF TREATMENT Russian patent published in 2011 - IPC A61K31/4409 A61K31/145 A61K9/00 A61K9/30 A61K9/02 A61J3/10 A61P31/06

Abstract RU 2423977 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to field of chemical-pharmaceutical industry, namely to novel anti-tuberculosis medication. Claimed medication contains as active substance 4-thioureidoiminomethyperidinium perchlorate in effective and safe quantity and pharmaceutically acceptable auxiliary substances. Also claimed is method of its obtaining, which makes it possible to obtain target product with high yield. Novel medication, obtained by claimed method, possesses high tuberculostatic activity and low toxicity, preserves its stability in long-term storage.

EFFECT: invention can be used for treatment of all forms of pulmonary and extra-pulmonary tuberculosis, as well as in prophylaxis in composition of combined tuberculosis therapy.

12 cl, 8 tbl, 16 ex

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RU 2 423 977 C1

Authors

Gushchin Aleksandr Sergeevich

Vinogradova Tat'Jana Ivanovna

Jablonskij Petr Kazimirovich

Batjunin Gennadij Andreevich

Zabolotnykh Natal'Ja Vjacheslavovna

Vasil'Eva Svetlana Nikolaevna

Malygin Aleksej Vladimirovich

Dates

2011-07-20—Published

2010-04-20—Filed