FIELD: molecular biology, genetic therapy, medicine, oncology.
SUBSTANCE: invention relates to isolation of polypeptide from prostate that comprises the sequence SEQ ID NO: 327, and polynucleotide isolated from prostate tumor tissue encoding prostate tumor polypeptides and comprising the sequence SEQ ID NO: 225 or SEQ ID NO: 326. These polypeptides and polynucleotides expand the assortment of genetic agents used in vaccines and pharmaceutical compositions for prophylaxis and treatment of prostate cancer and for diagnosis and monitoring of such tumors.
EFFECT: valuable biological and medicinal properties of polypeptide and polynucleotide.
2 cl, 4 tbl, 8 dwg, 16 ex
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