FIELD: microbiology and immunology, in particular immunodiagnosis.
SUBSTANCE: atypical strain of melioidose Burkholderia pseudomallei-111-6-1 with altered phenotype defected with respect to synthesis of 8 antigen and acting as immunosuppressor is used as antigen for animal immunization. Immune serum is obtained after 2 immunization cycles of animal-producer with titer in gel immunodiffusion reaction not less than 1:128.
EFFECT: immune serum with increased specific activity.
2 tbl, 2 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR DIFFERENTIATION OF MALLEUS AND MELIOIDOSIS EXITANTS WITH PRECIPITATING ANTISERUM | 2006 |
|
RU2305557C1 |
| METHOD FOR PREPARING ERYTHROCYTIC DIAGNOSTIC ANTIGEN FOR DETECTING ACTINOBACILLUS MALLEI AND MELIOIDOSIS ANTIGEN ANTIBODIES | 2013 |
|
RU2540902C1 |
| STRAIN OF CULTURED HYBRID CELLS OF ANIMAL MUS MUSCULUS - PRODUCER OF MONOCLONAL ANTIBODIES TO THERMOSTABLE COMPONENT OF CAPSULE-LIKE SUBSTANCE OF MELIODOSIS PATHOGEN | 1997 |
|
RU2117042C1 |
| METHOD OF IMMUNOELECTROPHORETIC DIFFERENTIATION OF MELIOIDOSIS AND FAP AGENTS | 2008 |
|
RU2366715C1 |
| METHOD FOR DETERMINING BURKHOLDERIA MALLEI CAPSULAR ANTIGEN IMMUNOGENICITY LEVEL | 2005 |
|
RU2293993C1 |
| METHOD FOR QUICK-TEST DETECTING OF INTRA-HOSPITAL Burkholderia cepacia INFECTION AND ITS DIFFERENTIATION AGAINST OTHER SPECIES OF BURKCHOLDERIA AND PSEUDOMONAS | 2004 |
|
RU2281501C1 |
| METHOD OF DETERMINING ANTIGEN STRESS LIMIT STIMULATING PRODUCTION OF HUMORAL ANTIBODIES | 2008 |
|
RU2371196C1 |
| METHOD OF PREPARING PROTECTIVE GLYCOPROTEIN OF MELIOIDOSIS PATHOGEN | 1996 |
|
RU2109520C1 |
| METHOD FOR ACCELERATED LINE IMMUNOELECTROPHORESIS FOR BURKHOLDERIA DIFFERENTIATION | 2012 |
|
RU2496112C1 |
| METHOD FOR DETECTING CROSS-REACTING ANTIGENS OF THE AGENTS OF MELIOIDOSIS, GLANDERS, PLAGUE, TULAREMIA AND TUBERCULOSIS | 2004 |
|
RU2286576C2 |
