FIELD: pharmaceutical industry.
SUBSTANCE: according to proposed method sterilizable package deformable at compression designed for pharmaceutical product is made of multilayer foil tube including one or several layers of polypropylene and one or several layers of aluminum, and polypropylene bottle provided with cap. Bottle and cap differ in modulus of elastically. For sterilization, closed package is placed in autoclave, and temperature and pressure in autoclave are regulated as a function of time creating required pressure regulated by electronic devices controlled by computer. Pressure in autoclave is chosen to prevent deformation and breakage of package. Package, after treatment in autoclave at temperature equal to 120°C for at least 20 min, has no folds or breaks, and its compressibility remains sufficient for dispensing the product.
EFFECT: provision of package which can be sterilized in autoclave after filling.
10 cl, 6 dwg
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Authors
Dates
2005-04-27—Published
2000-05-26—Filed