GAMMA-INTERFERON INDUCTOR Russian patent published in 2005 - IPC

Abstract RU 2254861 C1

FIELD: medicine, pharmacology.

SUBSTANCE: invention relates to study for effect of niglisine representing a derivative of glycyrrhizic acid. Invention proposes an agent for induction of gamma-interferon under conditions in vitro and in vivo. Invention proposes glycyrrhizic acid penta-O-nicotinate as such agent that is known early as an anti-inflammatory agent and inhibitor of HIV reproduction. Niglisine in the range of concentrations 0.167-6 mcg/ml enhances significantly the secretion of gamma-interferon by blood mononuclear cells that will allow its using for non-specific protection of body.

EFFECT: valuable properties of gamma-interferon inductor.

1 tbl, 3 dwg

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RU 2 254 861 C1

Authors

Pokrovskij A.G.

Fedjuk N.V.

Abdullaev S.M.

Baltina L.A.

Tolstikov G.A.

Dates

2005-06-27—Published

2003-12-01—Filed