GAMMA-INTERFERON INDUCTOR Russian patent published in 2005 - IPC

Abstract RU 2254861 C1

FIELD: medicine, pharmacology.

SUBSTANCE: invention relates to study for effect of niglisine representing a derivative of glycyrrhizic acid. Invention proposes an agent for induction of gamma-interferon under conditions in vitro and in vivo. Invention proposes glycyrrhizic acid penta-O-nicotinate as such agent that is known early as an anti-inflammatory agent and inhibitor of HIV reproduction. Niglisine in the range of concentrations 0.167-6 mcg/ml enhances significantly the secretion of gamma-interferon by blood mononuclear cells that will allow its using for non-specific protection of body.

EFFECT: valuable properties of gamma-interferon inductor.

1 tbl, 3 dwg

Similar patents RU2254861C1

Title	Year	Author	Number
SYNERGETIC COMPOSITION FOR INHIBITION OF HIV	2004	Pljasunova Ol'Ga Aleksandrovna Pokrovskij Andrej Georgievich Baltina Lidija Ashrafovna Tolstikov Genrikh Aleksandrovich	RU2272631C2
INHIBITOR OF HUMAN IMMUNODEFICIENCY VIRUS MULTIPLICATION	0	Pokrovskij Andrej Georgievich Plyasunova Olga Aleksandrovna Baltina Lidiya Ashrafovna Tolstikov Genrikh Aleksandrovich Murinov Yurij Ilich	SU1804848A1
RECOMBINANT PLASMIDE ENCODING HYBRID GST-ESAT-6 POLYPEPTIDE HAVING ACTIVITIES OF SPECIES-SPECIFIC MYCOBACTERIAL ESAT-6 ANTIGEN, RECOMBINANT ESCHERICHIA COLI STRAIN AS PRODUCER OF HYBRID GST-ESAT-6 POLYPEPTIDE AND RECOMBINANT GST-ESAT-6 POLYPEPTIDE	2004	Tumanov Jurij Vasil'Evich Smirnova Ol'Ga Jur'Evna Boldyrev Aleksandr Nikolaevich Tat'Kov Sergej Ivanovich	RU2282661C2
STRAIN OF HYBRID CULTIVATED CELLS OF MUS MUSCULUS ANIMALS USED FOR PRODUCING MONOCLONAL ANTIBODIES FOR CA TWO PLUS - ATPHASE OF SARCOPLASMATICRETICULUM OF DOG HEART	0	Cherepakhin Vladimir Viktorovich Syrbu Sergej Ivanovich Rokhlin Oskar Vulfovich Levitskij Dmitrij Olegovich Loginov Vasilij Anatolevich Popovich Mikhail Ilich	SU1414870A1
HYBRID CELL STRAIN OF MUS MUSCULUS 13F8 ANIMALS - PRODUCER OF MONOCLONAL ANTIBODIES SPECIFIC TO CAPSULAR F1 ANTIGEN YERSINIA PESTIS	2011	Belova Elena Valentinovna Ivashchenko Tat'Jana Aleksandrovna Ignashina Evgenija Nikolaevna Shemjakin Igor' Georgievich	RU2460788C1
HYBRID CELL STRAIN OF MUS MUSCULUS ANIMALS 10G4 - PRODUCER OF MONOCLONAL ANTIBODIES SPECIFIC TO CAPSULAR F1 ANTIGEN YERSINIA PESTIS	2011	Belova Elena Valentinovna Ivashchenko Tat'Jana Aleksandrovna Ignashina Evgenija Nikolaevna Shemjakin Igor' Georgievich	RU2460787C1
STRAIN OF CULTIVABLE HYBRID MUS MUSCULUS CELLS FOR PRODUCING MONOCLONAL ANTIBODIES TO HUMAN INTERLEUKIN	0	Ovchinnikov Yurij Anatolevich Lunev Vitalij Evgenevich Nesmeyanov Vladimir Andreevich Kazennykh Natalya Vladimirovna Belyaev Sergej Vasilevich Tsimanis Aleksandr Yurevich Onoprienko Lyudmila Viktorovna Mikhaleva Inessa Ivanovna	SU1472499A1
MUS MUSCULUS HYBRID CULTIVATED ANIMAL CELLS STRAIN α - THE PRODUCER OF MONOCLONAL ANTIBODIES SPECIFIC TO THE CANCER-TESTICULAR ANTIGEN OF THE PERSON GAGE	2017	Finashutina Yuliya Pavlovna Golubtsova Natalya Valerevna Baryshnikova Mariya Anatolevna Misyurin Andrej Vitalevich Shprakh Zoya Sergeevna	RU2652885C1
MONOCLONAL ANTIBODIES AND ONE-CHAIN FRAGMENTS OF CELL-SURFACE PROSTATE-SPECIFIC MEMBRANE ANTIGEN ANTIBODIES	2006	Ehl'Zehsserbajle Ursula Vol'F Filipp Girshner Dorotee Bjuler Patrik Vetterauer Ul'Rikh	RU2458073C2
DI- AND TRINICOTINATES OF GLYCYRRHIZIC ACID AND INHIBITOR OF HUMAN IMMUNODEFICIENCY VIRUS REPRODUCTION	2006	Tolstikov Genrikh Aleksandrovich Baltina Lidija Ashrafovna Volcho Konstantin Petrovich Pljasunova Ol'Ga Aleksandrovna Pokrovskij Andrej Georgievich Salakhutdinov Nariman Faridovich	RU2304145C1

RU 2 254 861 C1

Authors

Pokrovskij A.G.

Fedjuk N.V.

Abdullaev S.M.

Baltina L.A.

Tolstikov G.A.

Dates

2005-06-27—Published

2003-12-01—Filed