FIELD: biotechnology.
SUBSTANCE: invention relates to the field of biotechnology, in particular to hybridoma technology, and is a strain of hybrid cells of mus musculus α – producer of monoclonal antibodies to the human cancer-testicular antigen GAGE. Strain is deposited in the All-Russian Collection of Industrial Microorganisms FSUE State Research Institute of Genetics of the Ministry of Education and Science of the Russian Federation (BRC VKPM) under the number N-174.
EFFECT: invention makes it possible to obtain highly specific monoclonal antibodies that can be used in experimental oncology to study the structural and functional properties of GAGE family proteins in cell cultures and clinical samples.
1 cl, 3 dwg, 2 tbl, 3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| MUS MUSCULUS'S HYBRID CULTURE CELL STRAIN α PRODUCING MONOCLONAL ANTIBODIES SPECIFIC TO HUMAN GRANULOCYTE COLONY-STIMULATING FACTOR (GCSF) | 2013 |
|
RU2542381C2 |
| METHOD FOR PRODUCTION OF THE RECOMBINANT HUMAN PROTEIN GAGE1 | 2016 |
|
RU2652890C1 |
| STRAIN OF HYBRID CULTIVATED CELLS OF ANIMALS Mus Musculus, PRODUCING MONOCLONAL ANTIBODIES, SPECIFIC TO PEPTIDE, WHICH POSSESSES APOPTOTIC ACTIVITY WITH RESPECT TO CANCER CELLS | 2009 |
|
RU2402605C1 |
| STRAIN OF HYBRID ANIMAL CELLS Mus MUSCULUS 1F1 - PRODUCER OF A MONOCLONAL ANTIBODY AGAINST THE NUCLEOCAPSID PROTEIN N OF THE SARS-CoV-2 VIRUS | 2021 |
|
RU2769817C1 |
| MEDICINAL PREPARATION TO PREVENT TRANSPLANT DETACHMENT, MONOCLONAL ANTIBODY TO CD3 ANTIGEN OF HUMAN T-LYMPHOCYTES, HYBRIDOME AND METHOD TO TREAT PATIENTS SUFFERING ACUTE TRANSPLANT DETACHMENT REACTION FOLLOWING KIDNEY TRANSPLANTATION | 2000 |
|
RU2179862C1 |
| STRAIN OF HYBRID CULTIVATED MURINE CELLS Mus Musculus - 4F11 PRODUCING MONOCLONAL ANTIBODY RESPONDER WITH HEMAGGLUTININ PROTEIN OF HIGH-PATHOGEN STRAIN virus A/duck/Novosibirsk/56/05 H5N1 | 2008 |
|
RU2384617C1 |
| STRAIN OF HYBRID ANIMAL CELLS MUS MUSCULUS 2E1B5 - PRODUCER OF A MONOCLONAL ANTIBODY AGAINST THE RECEPROT-BINDING DOMAIN OF PROTEIN S OF THE SARS-CoV-2 VIRUS | 2021 |
|
RU2771288C1 |
| STRAINS OF HYBRID CELLS OF ANIMALS MUS_ MUSCULUS - PRODUCERS OF MONOCLONAL ANTIBODIES TO PROTEIN GP OF EBOLA VIRUS (SUBTYPE ZAIRE) AND MONOCLONAL ANTIBODIES TO PROTEIN GP OF EBOLA VIRUS (SUBTYPE ZAIRE) | 2017 |
|
RU2686630C1 |
| CULTIVATED HYBRID CELL STRAIN OF MOUSE Mus. Musculus-1E7 PRODUCER OF MONOCLONAL ANTIBODY IMMUNORESPONSIVE TO HAEMAGGLUTININ PROTEIN OF PANDEMIC INFLUENA VIRUS A/IIV-Moscow/01/09(H1N1)sw1 | 2011 |
|
RU2457243C1 |
| STRAIN OF THE HYBRID CULTURED MAMMALIAN CELLS MUS MUSCULUS L - A PRODUCER OF MONOCLONAL ANTIBODIES TO A-DETERMINANT OF HEPATITIS B VIRUS SURFACE ANTIGEN | 1994 |
|
RU2097426C1 |
