FIELD: veterinary microbiology, virology, biotechnology.
SUBSTANCE: invention proposes vaccine that comprises as antigens the following components, vol. %: inactivated suspension of cells of hemolytic strains of microorganism M. bovis with the total concentration 100-120 billion cells in 1 cm3: strain M. bovis "G97-VNIVI", 4.0-5.0; strain M. bovis "SHZ-01", 4.0-5.0; inactivated cultural suspension of the strain Herpesvirus bovis type I "TKA-VIEV-V2" with infectious titer 107.0 - 107.5 TCD50/ml, 78.0-83.0; 6% solution of aluminum hydroxide gel, the balance. Vaccine enhances accumulation of specific protective antibodies in serum blood of vaccinated animals and provides the development of immunity against infectious keratoconjunctivitis that is retained for one year.
EFFECT: enhanced effectiveness and valuable properties of vaccine.
4 tbl, 6 ex
| Title | Year | Author | Number |
|---|---|---|---|
| VACCINE AGAINST INFECTIOUS BOVINE KERATOCONJUNCTIVITIS BASED ON ANTIGENS OF Moraxella bovis and Moraxella bovoculi BACTERIA | 2015 |
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RU2589819C1 |
| STRAINS OF BACTERIA Moraxella bovoculi "SH-CH6 N-DEP" USED TO MANUFACTURE DIAGNOSTIC PREPARATIONS AND VACCINES AGAINST INFECTIOUS KERATOCONJUNCTIVITIS OF CATTLE | 2013 |
|
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| STRAIN OF BACTERIUM MORAXELLA BOVIS "G97-VNIVI" USED FOR PREPARING DIAGNOSTICA AND VACCINES AGAINST INFECTIOUS KERATOCONJUNCTIVITIS IN CATTLE | 1998 |
|
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| IMMUNE-ENZYME TEST SYSTEM FOR DETERMINING SPECIFIC ANTIBODIES TO MORAXELLA BOVOCULI BACTERIA IN BOVINE BLOOD SERUM | 2018 |
|
RU2687747C1 |
| METHOD OF PREVENTION OF INFECTIOUS CONJUNCTIVITIS-KERATITIS OF CATTLE | 2012 |
|
RU2517119C1 |
| INACTIVATED EMULSION VACCINE ASSOCIATED AGAINST ADENOVIRAL, HERPES VIRUS INFECTION, PARAINFLUENZA-3 AND VIRAL DIARRHEA - MUCOSAL DISEASE OF CATTLE | 2012 |
|
RU2517733C1 |
| PREPARATION FOR PREVENTING INFECTIOUS KERATOCONJUNCTIVITIS IN CATTLE AND METHOD FOR PREVENTING THIS DISEASE | 2000 |
|
RU2240820C2 |
| INACTIVATED EMULSION ASSOCIATED VACCINE FOR PARVOVIRAL, RHEOVIRAL, TYPE I HERPES-VIRAL INFECTIONS AND VIRAL DIARRHOEIA - CATTLE MUCOSAL DISEASE | 2010 |
|
RU2452512C2 |
| MIXED VACCINE AGAINST ROTA-, CORONA-, HERPESVIRAL AND ESCHERICHIA DIARRHEA IN NEWBORN CALVES | 1999 |
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| SERUM AGAINST CATTLE DISEASES CAUSED BY VIRUSES OF INFECTIOUS RHINOTRACHEATIS, PARAFLU, ROTA, CORONA AND MUCOSA DIARRHEA-DISEASE, POLYSPECIFIC, HYPERIMMUNE, METHOD OF PREVENTION AND TREATMENT OF CATTLE DISEASES CAUSED BY VIRUSES OF INFECTIOUS RHINOTRACHEITIS, PARAINFLUENZA, ROTA, CORONA AND MUCOSA DIARRHEA-DISEASE | 2010 |
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