METHOD FOR ASSAY OF INDIVIDUAL SENSITIVITY TO CALCIUM ANTAGONIST AND ANGIOTENSIN-CONVERTING ENZYME INHIBITOR IN ARTERIAL HYPERTENSION Russian patent published in 2005 - IPC

Abstract RU 2264625 C2

FIELD: medicine, biochemical pharmacology, cardiology.

SUBSTANCE: method involves determination of serum blood lipid hydroperoxides level and vascular tonus coefficient (VTC) is calculated. Favorable prognosis for effective using preparations related to angiotensin-converting inhibitors is determined at the VTC value <1.0 and indices of lipid hydroperoxides <4.5 U/l. At VTC value ≥1.0 and the concentration of lipid hydroperoxides ≥4.5 U/l prognosis for using preparations of angiotensin-converting enzyme inhibitor is considered to be unfavorable and prescription of preparations of calcium antagonists group is expediently. Invention proposes a new method for assay of diagnostic criteria for prescription of angiotensin-converting enzyme inhibitors and calcium antagonists.

EFFECT: improved assay method.

2 ex

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RU 2 264 625 C2

Authors

Batishcheva G.A.

Chernov Ju.N.

Goncharova N.Ju.

Ushakov I.B.

Kaljuzhnaja A.S.

Mitichkin A.V.

Chernov S.Ju.

Dates

2005-11-20Published

2003-12-23Filed