FIELD: chemical-pharmaceutical industry, pharmacy.
SUBSTANCE: invention relates to a method for preparing an antibacterial agent. Method involves mixing active components - ampicillin trihydrate and oxacillin sodium salt, and starch as a vehicle and filling gelatin capsules with the prepared mixture. Method involves separate mixing each active component with half of potato starch and following their combination, addition of lactose and powdering with aerosil. Then the prepared dry mixture is added into gelatin capsules that are covered preliminary by gelatinized potato starch layer from the interior of capsule and dried with inert gas at the rate of gas feeding 3-5 m/s. Method provides simplifying preparing capsulated preparations due to facility filling capsules and to enhance stability of the preparation in storing.
EFFECT: improved preparing method, improved properties of preparation.
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Authors
Dates
2005-12-20—Published
2004-05-19—Filed