METHOD FOR PRODUCTION OF DIAGNOSTICUM FOR DETERMINATION OF GENUS KLEBSIELLA BACTERIUM ENDOTOXIN Russian patent published in 2005 - IPC

Abstract RU 2266136 C2

FIELD: medicine, veterinary and food processing industry.

SUBSTANCE: claimed method includes manufacturing of corn-shell-type latex, wherein corn represents polystyrene latex and shell represents styrene-zinc methacrylate copolymer latex in repeating unit mass ratio of 1:0.8-1:0.4. Then latex is sensitized with monoclonal antibodies of lgG2a and lgG2b fractions in 0.01 M glycine buffer at pH 7.2-8.8 without preliminary conditioning followed by incubation primarily at 37°C for 130-150 min and further at 8°C for 18 hours. Obtained diagnosticum has specificity of 97±0.6, sensibility up to 10 pg/ml and makes it possible to obtain investigation results for 10 min or less.

EFFECT: accelerated method for diagnosticum production.

3 tbl

Similar patents RU2266136C2

Title Year Author Number
METHOD FOR PRODUCTION OF DIAGNOSTICUM FOR DETERMINATION OF GENUS ENTEROBACTER BACTERIUM ENDOTOXIN 2003
  • Bokerija L.A.
  • Nijazmatov A.A.
RU2266134C2
METHOD FOR PRODUCTION OF DIAGNOSTICUM FOR DETERMINATION OF GENUS SERRATIA BACTERIUM ENDOTOXIN 2003
  • Bokerija L.A.
  • Nijazmatov A.A.
RU2266135C2
METHOD FOR PRODUCTION OF DIAGNOSTICUM FOR DETERMINATION OF GENUS PSEUDOMONAS BACTERIUM ENDOTOXIN 2003
  • Bokerija L.A.
  • Nijazmatov A.A.
RU2266133C2
METHOD FOR PRODUCTION OF DIAGNOSTICUM FOR DETERMINATION OF TOTAL GRAM-NEGATIVE BACTERIUM ENDOTOXIN 2003
  • Bokerija L.A.
  • Nijazmatov A.A.
RU2266137C2
METHOD OF PREPARING THE STAINED DIAGNOSTICUM USED FOR ASSAY OF ANTIGENS AND ANTIBODIES OF INFECTIOUS AND OTHER SICKNESSES 1992
  • Nijazmatov A.A.
  • Chechik O.S.
RU2110526C1
METHOD OF PREPARING THE DIAGNOSTICUM USED FOR ASSAY OF ANTIGENS AND ANTIBODIES OF INFECTIOUS AND OTHER SICKNESSES 1992
  • Nijazmatov A.A.
  • Chechik O.S.
RU2110525C1
METHOD OF PREPARING THE DIAGNOSTICUM USED FOR ASSAY OF ANTIGENS AND ANTIBODIES OF INFECTIOUS AND OTHER SICKNESSES 1992
  • Nijazmatov A.A.
  • Chechik O.S.
RU2110527C1
LEGIONELLA DIAGNOSTICUM AND METHOD FOR PRODUCING IT 1995
  • Eruslanov B.V.
  • Borzenkov V.N.
  • Pecherskikh Eh.I.
  • Svetoch Eh.A.
RU2124208C1
DIAGNOSTICUM FOR DETERMINING PAPRIN LEVEL AND PROCESS OF PREPARING THEREOF 1991
  • Parfenova E.V.
  • Prokopov N.I.
  • Cherkasov V.R.
RU2008020C1
DIAGNOSTICUM FOR IDENTIFICATION OF ESCHERICHIA COLI 0157:H7 AND METHOD OF ITS PREPARING 2001
  • Eruslanov B.V.
  • Svetoch Eh.A.
  • Gusev V.V.
  • Stepanshin Ju.G.
  • Borzenkov V.N.
RU2189253C1

RU 2 266 136 C2

Authors

Bokerija L.A.

Nijazmatov A.A.

Dates

2005-12-20Published

2003-07-17Filed