METHOD FOR TREATMENT OF PATIENTS WITH CHRONIC RENAL INSUFFICIENCY Russian patent published in 2006 - IPC A61K31/95 A61P13/12 A61M1/34 

FIELD: medicine, nephrology.

SUBSTANCE: invention proposes a method for treatment of patients with chronic renal insufficiency and receiving treatment by renal dialysis or hemodiafiltration. Increase concentration of blood homocysteine in such patients causes the severe disturbances in vessels function and represents risk factor for vascular diseases. Method involves prescription of dithiothreitol or 2,3-dimercaptopropane sodium sulfonate (unithiol) before or during hemodialysis or hemofiltration. Method provides reducing blood level of homocysteine in patients in case of its increased content (in these patients the concentration of low- and mean-molecular metabolic products is increased sharply due to damage or complete ceasing formation of urine) to practically normal values that is based on release of homocysteine from its bound form with proteins.

EFFECT: improved treatment method of patients.

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