STABLE PERORAL SOLID COMPOSITION OF MEDICINAL PREPARATION Russian patent published in 2006 - IPC A61K31/4184 A61K9/14 A61K9/20 A61K47/02 A61K47/12 A61K47/14 A61K47/18 A61K47/22 A61K47/30 A61K47/38 A61P1/00 A61P25/00 A61P43/00 

Abstract RU 2284819 C2

FIELD: medicine.

SUBSTANCE: the present innovation deals with stable peroral solid composition of ramosetron or its pharmaceutically acceptable salt. The composition includes one or several components chosen out of the groups including aliphatic carboxylic acid or its ester, hydroxycarboxylic acid or its ester, acidic amino acid, enolic acid, aromatic carboxylic compound or its ester and high-molecular substance that contains carboxylic group. Such an innovation refers to the method for stabilizing ramosetron composition. The suggested innovation provides stability of ramosetron composition under conditions of increased temperature and humidity, especially at low content of active component.

EFFECT: higher efficiency of application.

14 cl, 10 ex, 6 tbl

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RU 2 284 819 C2

Authors

Sugikhara Akio

Masaki Katsukhiro

Jasudzi Takekhiko

Nisida Akito

Niva Akira

Atsuta Jutaka

Dates

2006-10-10Published

2004-01-30Filed