PHARMACEUTICAL COMPOSITION DISTINGUISHED BY PROLONGED RELEASE INDEPENDENT OF IONIC FORCE Russian patent published in 2006 - IPC A61K9/26 A61K31/496 A61K45/06 A61K47/38 A61P9/00 A61P25/00 

Abstract RU 2285519 C2

FIELD: medicine.

SUBSTANCE: composition comprises gel-forming matrix having one or more active ingredients with prolonged release time of one or more active substances under gastrointestinal tract fluids action. Hydroxypropylmethyl cellulose of high or moderate viscosity or hydroxyethyl cellulose of high or moderate viscosity are available in the composition in 1:0.85-1:1.2 proportion, respectively. The composition optionally comprises also hydroxypropylmethyl cellulose of low viscosity with hydroxypropylmethyl cellulose of low viscosity to one of high or moderate viscosity proportion being equal to 1:0.01-1.0.2, respectively. The composition essentially does not depend on ionic force of dissolving medium habitual for gastrointestinal tract fluids as norm even if the composition is not enclosed into coating shell.

EFFECT: enhanced effectiveness of treatment.

12 cl, 4 tbl

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RU 2 285 519 C2

Authors

Gorissen Khenrikus R.M.

Frejlink Khenderik V.

Dates

2006-10-20Published

2001-09-28Filed