FIELD: medicinal and pharmaceutical industry.
SUBSTANCE: method involves mixing polyphepan with a binding agent, drying a mixture and tabletting. Lactose is used as a binding, slipping and lubricating agent. After mixing components the prepared mixture is granulated and wetted granules are fed for drying up to residual moisture value 8%, not above. After drying termination granules are milled to particles size less 3.0 mm and then crushed granules are fed for tabletting and tablets with weight 0.5 g (± 0.025 g) are made of the following composition, g: polyphepan (as measure for dry matter), 0.35-0.40, and lactose, the balance. Invention provides retaining the sorption activity of polyphepan and to simplify the process.
EFFECT: improved preparing method.
1 ex
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Authors
Dates
2006-10-20—Published
2005-06-15—Filed