DESMOPRESSIN MEDICINAL FORMULATION DISPERSED IN MOUTH CAVITY Russian patent published in 2007 - IPC A61K38/11 A61K9/20 A61K47/26 A61K47/36 A61K47/42 A61P7/12 

FIELD: medicine, pharmacy.

SUBSTANCE: invention relates to preparations, methods for their preparing and using in treatment and prophylaxis of diseases. Invention relates to a pharmaceutical medicinal formulation decomposing into mouth for 10 s and prepared by sublimation of a solvent from the composition comprising desmopressin acetate and sugar and gelatin solvent in a solvent. Also, invention proposes a method for preparing this medicinal formulation. Method involves sublimation of a solvent from the composition comprising desmopressin and sugar and gelatin solution wherein this composition for preparing the medicinal formulation is in the solid state. Also, invention relates to using desmopressin acetate for preparing the claimed formulation used in empty delaying, treatment or prophylaxis of irretention, primary nocturnal enuresis, nycturia or diabetes insipidus of the central nervous system origin. Also, invention proposes a package comprising the claimed medicinal formulation and instruction for its using. The claimed medicinal formulation and method for its using provide enhancing the bioavailability of desmopressin.

EFFECT: improved and valuable properties of formulation.

17 cl, 11 ex