FIELD: pharmacology.
SUBSTANCE: group of inventions is a method for preparation of a medicament comprising administration of a liquid preparation containing a pharmaceutically active ingredient, levan and inulin in a solvent, into the recesses of the blister pack, sublimation of the solvent from the preparation by freeze-drying to form solid unit dosage forms and sealing of the blister pack recesses by a sealing film or a foil, as well as a medicinal product obtained by the above method containing solid units dosage forms in a blister pack, wherein the dosage form comprises an open matrix network structure carrying the pharmaceutically active ingredient and containing levan and inulin.
EFFECT: inventions permit preparation of a drug with a high rate of dissolution in the aqueous medium or saliva, having a low tensile strength, which makes it easy to extract it from the package.
20 cl, 31 tbl, 30 ex
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RU2372074C2 |
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| COMPOSITIONS AND METHODS OF ACTIVE PHARMACEUTICAL INGREDIENT STABILISATION | 2005 |
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RU2391115C2 |
| LYOPHILIZED PHARMACEUTICAL COMPOSITIONS FOR VAGINAL DELIVERY | 2017 |
|
RU2753864C2 |
Authors
Dates
2017-10-16—Published
2012-09-07—Filed