PHARMACEUTICAL COMPOSITION FOR TREATMENT OF FUNGAL DISEASE AND METHOD FOR ITS PREPARING Russian patent published in 2007 - IPC A61K31/425 A61K9/06 A61P31/10 

FIELD: medicine, pharmacy, fungicides.

SUBSTANCE: invention relates to a novel pharmaceutical composition as an ointment used in treatment of fungal diseases. Proposed composition comprises 3-methoxycarbonyl-5-(4-chlorobenzylidene)-thiazolidine-2,4-dione as active substance. Ointment comprises solid petroleum paraffin, stearic acid, vaseline oil and emulsion wax as a lipophilic base and benzoic acid as special additive. Pharmaceutical composition is prepared by fusion of solid components of a base followed by addition of 3-methoxycarbonyl-5-(4-chlorobenzylidene)-thiazolidine-2,4-dione concentrate in vaseline oil. Invention provides preparing pharmaceutical composition possessing high chemotherapeutic effectiveness and good tolerance and low toxicity that allows its using in treatment of dermatomycosis of different localization.

EFFECT: valuable medicinal properties of pharmaceutical composition.

2 cl, 2 tbl, 4 ex