PHARMACEUTICAL COMPOSITION FOR TREATING MYCOTIC DISEASES Russian patent published in 2015 - IPC A61K31/425 A61K9/06 A61K47/12 A61K47/44 A61K47/16 A61P31/10 

FIELD: medicine.

SUBSTANCE: as an active substance, a formulation according to the invention contains 3-ethoxyxycarbonyl-5-(4-chlorobenzylidene)thiazolidine-2,4-dione 2-5 wt %, and also the pharmaceutical composition is expected to contain carbamide in an amount of 2.5-4.0 wt %, as a keratolytic agent. The ointment also contains a lipophilic base that is petroleum paraffin wax in an amount of 5-7 wt %, stearic acid 2-6.5 wt %, emulsion wax 8-12 wt %, a target additive - benzoic acid 0.1-2 wt % and Vaseline oil up to 100%. The pharmaceutical formulation is produced by fusing the solid ingredients of the base, adding concentrated 3-ethoxyxycarbonyl-5-(4-chlorobenzylidene)thiazolidine-2,4-dione in Vaseline oil and carbamide in Vaseline oil.

EFFECT: producing the pharmaceutical formulation possessing the high chemotherapeutic efficacy and good tolerance, low toxicity that makes it applicable in treating dermatomycosis of different localisation.

2 cl, 3 tbl