FIELD: medicine, pharmaceutical industry.
SUBSTANCE: claimed method includes vacuum sublimation from solid layer of frozen suspension of thermolabile biologically active preparation; initially at irradiator temperature, which is at least 20°C higher than maximum critical temperature (+36°C)-(+60°C) and doesn't induce thermal inactivation of thermolabile biologically active preparation, up to experientially determined preparation temperature (+25°C)-(+35°C), wherein thermolabile biologically active preparation is not inactivated during irradiator temperature decrease. Then material is dried again at (+36°C)-(+60°C).
EFFECT: accelerated method of increased productivity; dried preparation of improved quality.
3 ex
| Title |
Year |
Author |
Number |
| METHOD OF PELLETISATION OF MEDICINAL IMMUNOBIOLOGICAL PREPARATIONS |
2006 |
- Davydkin Igor' Jur'Evich
- Aleshkin Vladimir Andrianovich
- Davydkin Valerij Jur'Evich
- Rubal'Skij Oleg Vasil'Evich
- Gavrin Andrej Gennad'Evich
- Melikhova Aleksandra Vadimovna
- Afanas'Ev Stanislav Stepanovich
|
RU2334503C1 |
| CONSORTIUM OF BIFIDOBACTERIA AND LACTOBACILLI USED FOR PREPARING BACTERIAL PREPARATIONS, FERMENTS FOR FERMENTED-MILK FOODSTUFFS, FERMENTED AND NONFERMENTED FOODSTUFFS, BIOLOGICALLY ACTIVE SUPPLEMENTS DESIGNATED FOR CORRECTION OF MICROFLORA IN HUMANS IN AGE FROM 12 YEARS AND OLDER |
2001 |
- Aleshkin V.A.
- Amerkhanova A.M.
|
RU2180914C1 |
| BIFIDOBACTERIUM AND LACTOBACILLUS CONSORTIUM USED FOR PREPARING BACTERIAL PREPARATIONS, FERMENTS FOR FERMENTED-MILK FOODSTUFFS, FERMENTED AND NONFERMENTED FOODSTUFFS, BIOLOGICALLY ACTIVE SUPPLEMENTS DESIGNATED FOR CORRECTION OF MICROFLORA IN CHILDREN OF AGE FROM 3 TO 12 YEARS |
2001 |
- Aleshkin V.A.
- Amerkhanova A.M.
|
RU2180348C1 |
| METHOD FOR SPRAY DRYING OF BIOLOGICALLY ACTIVE PREPARATION |
2006 |
- Aleshkin Vladimir Andrianovich
- Davydkin Valerij Jur'Evich
- Davydkin Igor' Jur'Evich
- Rubal'Skij Oleg Vasil'Evich
- Afanas'Ev Stanislav Stepanovich
- Gavrin Andrej Gennad'Evich
|
RU2299062C1 |
| BIFIDOBACTERIAL AND LACTOBACILLARY CONSORTIUM FOR PREPARING BACTERIAL PREPARATIONS AND DIETARY SUPPLEMENTS FOR CORRECTING GASTROINTESTINAL MICROFLORA IN CHILDREN AGED FROM THREE TO FOURTEEN, AND METHOD FOR PREPARING IT, DIETARY SUPPLEMENT AND BACTERIAL PREPARATION FOR TREATING DYSBIOTIC GASTROINTESTINAL CONDITIONS IN CHILDREN AGED FROM THREE TO FOURTEEN |
2012 |
- Amerkhanova Adelaida Mikhajlovna
- Aleshkin Andrej Vladimirovich
- Zhilenkova Ol'Ga Gennad'Evna
|
RU2491335C1 |
| BIFIDOBACTERIAL AND LACTOBACILLARY CONSORTIUM FOR PREPARING BACTERIAL PREPARATIONS AND DIETARY SUPPLEMENTS FOR CORRECTING GASTROINTESTINAL MICROFLORA IN CHILDREN UNDER AGE OF THREE, AND METHOD FOR PREPARING IT, DIETARY SUPPLEMENT AND BACTERIAL PREPARATION FOR TREATING DYSBIOTIC GASTROINTESTINAL CONDITIONS IN CHILDREN UNDER AGE OF THREE |
2012 |
- Amerkhanova Adelaida Mikhajlovna
- Aleshkin Andrej Vladimirovich
- Zhilenkova Ol'Ga Gennad'Evna
|
RU2491331C1 |
| BIOPREPARATION FOR ADULTS USEFUL IN PROPHYLAXIS AND TREATMENT OF DYSBACTERIOSIS AND INFECTIVE DISEASES OF GASTROINTENSTINAL TRACT IN HUMAN OF 12 YEARS OLD OR MORE |
2003 |
- Amerkhanova A.M.
- Aleshkin V.A.
- Zubkova E.S.
|
RU2264450C2 |
| BIOPREPARATION USEFUL IN PROPHYLAXIS AND TREATMENT OF DYSBACTERIOSIS AND INFECTIVE DISEASES OF GASTROINTENSTINAL TRACT IN CHILDREN OF 3 - 12 YEARS OLD |
2003 |
- Amerkhanova A.M.
- Aleshkin V.A.
- Zubkova E.S.
|
RU2264452C2 |
| CONSORTIUM OF BIFIDOBACTERIA AND LACTOBACILLI USED FOR PREPARING BACTERIAL PREPARATIONS, FERMENTS FOR FERMENTED-MILK FOODSTUFFS, FERMENTED AND NONFERMENTED FOODSTUFFS, BIOLOGICALLY ACTIVE SUPPLEMENTS DESIGNATED FOR CORRECTION OF MICROFLORA IN CHILDREN IN AGE BELOW 3 YEARS |
2001 |
- Aleshkin V.A.
- Amerkhanova A.M.
|
RU2180915C1 |
| METHOD OF COMBINATION DEHYDRATATION OF HIGH-DISPERSE BIOLOGICALLY ACTIVE MATERIALS |
2009 |
- Davydkin Valerij Jur'Evich
- Davydkin Igor' Jur'Evich
- Aleshkin Vladimir Andrianovich
- Melikhova Aleksandra Vadimovna
|
RU2440099C2 |
