INDOLE-2-CARBOXAMIDES AS INHIBITORS OF FACTOR Xa AND/OR VIIa, MEDICINAL AGENT BASED ON THEREOF AND METHOD FOR THEIR PREPARING Russian patent published in 2007 - IPC C07D209/42 C07D401/12 C07D401/14 C07D403/12 C07D409/14 C07D413/14 C07D417/14 A61K31/405 

Abstract RU 2299881 C2

FIELD: organic chemistry, medicine, hematology, pharmacy.

SUBSTANCE: invention relates to novel compounds of the formula (I): in all their stereoisomeric forms and their mixtures taken in any ratio and their physiologically acceptable salts possessing properties of inhibitors of factor Xa and/or factor VIIa, and to a medicinal agent based on thereof. Also, invention relates to a method for synthesis of these compounds and their using for preparing pharmaceutical agents for inhibition of activity of factor Xa and/or factor VIIa or for their effect on blood coagulation or fibrinolysis.

EFFECT: valuable medicinal properties of compounds and pharmaceutical composition.

10 cl, 1 tbl, 276 ex

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RU 2 299 881 C2

Authors

Nazare Mark

Ehssrikh Melani

Uill Dehvid Uill'Jam

Matter Khans

Ritter Kurt

Vener Fol'Kmar

Dates

2007-05-27Published

2002-11-08Filed