METHOD FOR TREATING HUMAN DISEASES ACCOMPANIED WITH INCREASED DNA CONTENT IN EXTRACELLULAR SPACES OF TISSUES AND MEDICINAL PREPARATION FOR ITS REALIZATION Russian patent published in 2007 - IPC A61K38/43 A61P37/00 A61P43/00 

FIELD: medicine.

SUBSTANCE: the present innovation deals with treating wide variety of diseases accompanied with increased DNA content in extracellular spaces of human tissues and organs such as: proliferative, for example, tumoral and hyperplastic processes; diseases of infectious origin; diseases being the result of atrophic, degenerative and inflammatory alterations in organs and tissues, for example, systemic lupus erythematosus. The method for therapy includes enteral introduction of DNAase enzyme at the dosages ranged 2000 up to 500000 Kunz U/kg body weight daily. Medicinal preparation for realization of this method contains DNAase enzyme the content of which in a single dosage corresponds to 50000 up to 5000000 Kunz U. It has been first established that enteral introduction of such high dosages of DNAase provides absorption of catalytically valuable quantities of this enzyme into the blood at significant increase of DNA-hydrolytic activity of the enzyme.

EFFECT: higher efficiency of therapy.

13 cl, 12 ex, 6 tbl