METHOD FOR TREATING SUTURED PERFORATED GASTRODUODENAL ULCERS Russian patent published in 2008 - IPC A61K33/00 A61K33/08 A61K33/14 A61K35/06 A61P1/04 

FIELD: medicine, gastroenterology, surgery.

SUBSTANCE: starting since the 2^nd d after operation it is necessary to have a daily twice peroral intake of 200-300 ml ozonized distilled water at ozone concentration being 4-6 mg/l and intragastric injection of ozone-oxygen mixture (OOM). On the 5-6^th d after operation in case of fibrogastroduodenoscopy (FGDS) it is important to inject per 4-5 ml ozonized physiological solution (OPS) at ozone concentration of 2-4 mg/l submucosally along the perimeter of the sutured ulcer, at about 4-5 mm against its edges, from 4 equidistant points. Then it is necessary to carry out ulcer's application with "Ozonide" oil. After that OOM should be injected at ozone concentration ranged 20-25 mg/l till the appearance of bulging out feeling in area of a patient's epigastrium. The above-mentioned procedures should be repeated every 3-4 d till complete ulcer's healing. The innovation shortens the terms of lysis of necrotic masses, improves reparative processes in the sutured wound and decreases inoculation degree with Helicobacter pylori in gastric and duodenal mucosa.

EFFECT: higher efficiency of therapy.

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