FIELD: medicine, pharmacy.
SUBSTANCE: invention proposes a hypotensive medicinal agent as tablet that comprises captopril, mixture of lactose of particles size above 0.2 mm and microcrystalline cellulose in the ratio from 73:1 to 49:25, respectively, and lubricating agent. Agent is made as a tablet of mass from 0.1 to 0.3 g with the content of captopril 25 or 50 mg. Invention provides making captopril tablets decomposing for 15 min and satisfying Pharmacopoeia requirements by all indices and showing stability in production and storage for 5 years.
EFFECT: improved and valuable pharmaceutical properties of agent.
3 cl, 1 dwg, 4 tbl, 6 ex
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Authors
Dates
2008-02-20—Published
2006-05-04—Filed