HYPOTENSIVE MEDICINAL AGENT Russian patent published in 2008 - IPC A61K31/401 A61K9/20 A61P9/12 

Abstract RU 2317079 C1

FIELD: medicine, pharmacy.

SUBSTANCE: invention proposes a hypotensive medicinal agent as tablet that comprises captopril, mixture of lactose of particles size above 0.2 mm and microcrystalline cellulose in the ratio from 73:1 to 49:25, respectively, and lubricating agent. Agent is made as a tablet of mass from 0.1 to 0.3 g with the content of captopril 25 or 50 mg. Invention provides making captopril tablets decomposing for 15 min and satisfying Pharmacopoeia requirements by all indices and showing stability in production and storage for 5 years.

EFFECT: improved and valuable pharmaceutical properties of agent.

3 cl, 1 dwg, 4 tbl, 6 ex

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RU 2 317 079 C1

Authors

Gavrilov Andrej Stanislavovich

Beketov Boris Nikandrovich

Zhujkova Natal'Ja Nikolaevna

Bakieva Natal'Ja Georgievna

Valigun Sergej Fedorovich

Zhorov Boris Mikhajlovich

Petrov Aleksandr Jur'Evich

Bratus' Elena Aleksandrovna

Dates

2008-02-20Published

2006-05-04Filed