FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to chemical-pharmaceutical industry and represents a method for preparing coated teriflunomide tablets characterised by selecting fractions of teriflunomide and additive ingredients, including a mixture of an excipient specified in lactose, calcium hydrophosphate, microcrystalline cellulose or a combination thereof, a desintegrant specified in sodium carboxymethyl starch, pre-gelled starch, and an anti-friction agent by sieving at an average sieve mesh of 0.14-0.20 mm, mixing to a homogenous state and forming a mixture into a tablet at extrusion pressure 15-20 kN/cm2 an coating with a film.
EFFECT: invention provides optimising the composition and process of preparing the tablets optimal characteristics of active agent release.
4 cl, 2 ex
| Title | Year | Author | Number |
|---|---|---|---|
| COMPOSITION FOR TREATING MULTIPLE SCLEROSIS (VERSIONS) | 2012 |
|
RU2493845C1 |
| PHARMACEUTICAL COMPOSITION CONTAINING DESLORATADINE (VERSIONS) | 2013 |
|
RU2537169C1 |
| SOLID PHARMACEUTICAL FORM OF IMMEDIATELY RELEASING ZAFIRLUKAST AND METHOD OF ITS PRODUCTION | 2016 |
|
RU2619213C1 |
| PHARMACEUTICAL ANTI-DIABETIC COMPOSITION BASED ON SUBSTITUTED THIOPHENE CARBOXYLATE AND A METHOD FOR PRODUCTION THEREOF | 2018 |
|
RU2688235C1 |
| DOSAGE FORM IN CAPSULE FORM CONTAINING TABLETS WITH DIMETHYL FUMARATE | 2019 |
|
RU2742745C1 |
| METHOD FOR PRODUCTION OF ANTIOXIDANT PREPARATION IN FORM OF TABLET | 2020 |
|
RU2749718C1 |
| DRUG BASED ON TETRAMETILTETRAAZOBITSIKLOOKTANDION AND METHOD FOR ITS PRODUCTION | 2012 |
|
RU2611194C2 |
| PHARMACEUTICAL COMPOSITION CONTAINING ZOLMITRIPTAN AND ITS PRODUCTION TECHNOLOGY | 2023 |
|
RU2813095C1 |
| SOLID DOSAGE FORM OF AVATROMBOPAG AND METHOD FOR PRODUCTION THEREOF | 2020 |
|
RU2769863C1 |
| PHARMACEUTICAL COMPOSITION OF MOXIFLOXACIN AND METHOD FOR PRODUCING IT | 2014 |
|
RU2558932C1 |
