FIELD: medicine.
SUBSTANCE: method involves estimating patient health state condition based on diagnostic cardiac rhythm variability data as intersystolic interval duration mean square deviation. The diagnostic index being equal to or less than 20 ms, Tophysopam is to be per os introduced at a dose of 50 mg 30 min before surgical intervention. The diagnostic index value being greater than 20 ms and less than 50 ms, Tophysopam is to be introduced at a dose of 25 mg 30 min before surgical intervention.
EFFECT: enhanced effectiveness of anesthesia; reduced risk of adverse vegetative cardiovascular system responses.
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