MEDICINAL AGENT POSSESSING NOOTROPIC ACTIVITY (VARIANTS) Russian patent published in 2008 - IPC A61K31/662 A61K47/00 A61K9/08 A61P25/28 

FIELD: medicine, pharmacy.

SUBSTANCE: invention proposes agent that possesses the nootropic activity and comprises dimephosphone as an active substance. Medicinal agent in form of an aqueous solution comprises additionally citric acid and lithium carbonate in the following ratio of components, wt.-%: dimephosphone, 15.0-30.0; lithium carbonate, 0.5-5.0; citric acid, 3.0-4.0, and deionized water, up to 100. Medicinal agent in form of syrup comprises the following composition, wt.-%: dimephosphone, 3.0-5.0; lithium carbonate, 1.0-1.2; citric acid, 4.0-5.0, and 64% sugar syrup, 89.0-92.0. Variants of the invention are syrup with the increased concentration of dimephosphone, and syrup comprising glycine additionally. Novel medicinal agents show physiological pH values elicited in the broad range of concentrations, stability of solutions in dilution, pleasant taste that simplified their using in pediatrics.

EFFECT: improved and valuable pharmaceutical properties of drug.

5 cl, 5 tbl, 1 dwg, 12 ex