CRYSTALLINE FORM OF DERIVATIVE OF 1,2-DIHYDROPYRIDINE AND METHOD FOR PREPARATION THEREOF Russian patent published in 2008 - IPC C07D213/64 C07D401/04 A61K31/444 A61P25/28 

Abstract RU 2323930 C1

FIELD: chemistry.

SUBSTANCE: invention relates to crystallic hydrate of 3-(2-cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridine-2-one of example В1, to method for preparation thereof, to anhydrous crystalline forms of 3-(2-cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridine-2-one of examples D1, С1, Е1, as well as to pharmaceutical composition. Technical effect - easy commercial preparation of 3-(2-cyanophenyl)-5-(2-pyridyl-1-phenyl-1,2-dihydropyridine-2-one as a homogeneous crystalline form, which is an АМРА receptor antagonist and/or kainate receptor inhibitor.

EFFECT: facilitation of dyhydropyridine preparation.

26 cl, 9 ex, 11 tbl

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RU 2 323 930 C1

Authors

Arimoto Itaru

Nagato Satosi

Sugaja Jukiko

Urava Josio

Ito Koiti

Naka Khirojuki

Omae Takao

Dates

2008-05-10Published

2005-07-05Filed