APPLICATION OF CYCLIC BIOISOSTER DERIVATIES OF PURINE SYSTEM FOR TREATMENT OF DISORDERS CAUSED BY ABNORMALITIES OF NITRERGIC AND DOPAMINERGIC SYSTEMS Russian patent published in 2008 - IPC C07D237/32 C07D471/06 C07D487/06 A61K31/5025 A61P25/18 A61P25/24 A61P25/30 

FIELD: medicine; veterinary science.

SUBSTANCE: invention refers to application of compounds with common structural formula

R¹=-H, -NH₂, -Br, -Cl, -ОН, -СООН,

B=-N=, -CH=, Z=-CH=, -N=,

A=-CH- at B=-N=, Z=-CH-,

A=-CH- at В=-СН=, Z=-CH=,

A=-N= at B=-N=, Z=-CH-,

A=-CH- at B=-N=, Z=-N=,

A=-CH= at В=-СН=, Z=-N=.

Structures of specified formula are active for nitrergic and dopaminergic systems of mammal body including human body. These compounds can be applied as neuroprotectors, to improve cognitive function and to normalise psychophysiologic state, to treat consequences of substance abuse, as well as to treat wide range of diseases including neuropsychic, cardiovascular, immune, inflammatory and gastro-intestinal disorders.

EFFECT: application of new and well-known compound to effect nitrergic and dopaminergic systems for treatment purposes.

4 ex, 3 tbl, 8 dwg