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(19)

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2 750 935

(13)

(51)

IPC

C07D495/04(2006-01-01)

C07D493/14(2006-01-01)

A61K31/395(2006-01-01)

A61K31/5025(2006-01-01)

(21) (22)

Application

2018142987, 2017-06-22

(24)

Start date

2017-06-22

(22)

Actual filing date

2017-06-22

(45)

Published

2021-07-06

(72)

Inventor

Lindsli, Krejg V.Konn, P. DzheffriEngers, Darren V.Bollinger, ShonTarr, Dzhejms S.Spiaring, PolEngers, Dzhuli L.Long, MadelinBridzhes, Tomas M.

(73)

Holder

Vanderbilt Yuniversiti

POSITIVE ALLOSTERIC MODULATORS OF MUSCARINIC ACETYLCHOLINE RECEPTOR M4 Russian patent published in 2021 - IPC C07D495/04 C07D493/14 A61K31/395 A61K31/5025

Abstract RU 2750935 C2

FIELD: biochemistry.

SUBSTANCE: invention relates to tricyclic compounds of formula (I) as well as their pharmaceutically acceptable salts.

EFFECT: new compounds, as well as pharmaceutical compositions based on them, and methods of treating neurological and/or mental disorders associated with dysfunction of the muscarinic acetylcholine receptor have been obtained.

21 cl, 11 tbl, 12 ex, 2 dwg

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RU 2 750 935 C2

Authors

Lindsli, Krejg V.

Konn, P. Dzheffri

Engers, Darren V.

Bollinger, Shon

Tarr, Dzhejms S.

Spiaring, Pol

Engers, Dzhuli L.

Long, Madelin

Bridzhes, Tomas M.

Dates

2021-07-06—Published

2017-06-22—Filed