METHOD OF PRODUCTION OF ANTI-INFECTIVE AGENT Russian patent published in 2008 - IPC A61K33/38 A61K33/34 A61K47/02 A61P31/04 

Abstract RU 2330673 C1

FIELD: medicine.

SUBSTANCE: invention refers to anti-infective materials (agents) and methods of production thereof, characterised by biocompatibility with animal or human body liquids and tissues. Invention concerns method of production of anti-infective agent, production of anti-infective agent implying modification of inorganic mineral with silico- and alumooxycompounds, namely, Na-shaped bentonite, inorganic metal salts in polar solvent, followed by bentonite keeping in salt solution, isolation of promodified bentonite from solution and drying at temperature not higher 100°C. Before being modified bentonite is enriched with Na+ ions through processing with 3-10% aqueous solution of chloride sodium with following washing and filtering of produced semiproduct thereafter modified by 10-20% inorganic metal salts solution represented with silver nitrate or copper sulphate. Modified bentonite is kept in specified salt solutions within 12-24 hour. Then promodified bentonite is cleared from sodium salts through washing and filtration. After being dried made agent is milled to particle dispersion 20-150 nm. Thus inorganic mineral are processed with specified solutions in ratio, weight fraction bentonite:solution, as 1: (10-40).

EFFECT: production of agent with higher anti-infective efficiency using simple and cheap methods and materials.

7 cl, 6 ex

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RU 2 330 673 C1

Authors

Abramjan Ara Arshavirovich

Beklemyshev Vjacheslav Ivanovich

Makhonin Igor' Ivanovich

Makhonin Petr Ivanovich

Solodovnikov Vladimir Aleksandrovich

Dates

2008-08-10Published

2006-11-22Filed