FIELD: chemistry.
SUBSTANCE: invention concerns a method of obtaining of amorphous calcium atorvastatin exhibiting hypolipidemic activity. The method involves dissolution of calcium atorvastin with subsequent precipitation by addition of the resulting solution to a mixture with a solvent precipitator, and filtration of the precipitated amorphous atorvastin.
EFFECT: obtaining amorphous calcium atorvastatin with high purity degree and high output.
5 ex
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Authors
Dates
2008-08-10—Published
2005-04-04—Filed