FIELD: medicine.
SUBSTANCE: invention is referred to medicine, in particular to experimental pharmacology. For realisation of risk prediction method of ulceration of gastroduodenal zone tissues, determine lipide structure of a blood plasma. Thus, the high risk of ulceration is defined at level of phospholipids 23.18±1.30% cholesterol 15.53±0.87%, and ethers of cholesterol 39.71±1.38%. The low risk of ulceration is defined at level of phospholipids 28.03±1.58%, cholesterol 22.36±1.22%, and ethers of cholesterol 33.04±2.33%. Tests of preparations with counter-ulcerogenic activity are recommended to be spent on the rats predisposed to an ulceration that allows estimating more objectively counter-ulcerogenic activity of tested preparations.
EFFECT: obtaining an effective way of risk predicition of gastroduodenal zone tissues ulceration.
7 tbl, 2 ex
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Authors
Dates
2008-10-27—Published
2006-12-25—Filed