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2 347 561

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IPC

A61K31/05(2006-01-01)

A61K31/135(2006-01-01)

A61P7/02(2006-01-01)

A61P7/06(2006-01-01)

(21) (22)

Application

2007115301/15, 2007-04-23

(24)

Start date

2007-04-23

(22)

Actual filing date

2007-04-23

(45)

Published

2009-02-27

(72)

Inventor

Plotnikov Mark BorisovichKrasnov Efim AvraamovichSmol'Jakova Vera IvanovnaIvanov Ivan SergeevichKuchin Aleksandr Vasil'EvichChukicheva Irina Jur'EvnaBuravlev Evgenij Vladimirovich

(73)

Holder

Gosudarstvennoe Uchrezhdenie Nauchno-Issledovatel'Skij Institut Farmakologii Tomskogo Nauchnogo Tsentra Sibirskogo Otdelenija Rossijskoj Akademii Meditsinskikh Nauk Nii Farmakologii Tnts So Ramn)Institut Khimii Komi Nauchnogo Tsentra Ural'Skogo Otdelenija Rossijskoj Akademii Nauk Khimii Komi Nts Uro Ran)Plotnikov Mark Borisovich

AGENTS WITH HEMORHEOLOGICAL, ANTIAGGREGANT AND ANTITROMBOGENIC ACTIVITY Russian patent published in 2009 - IPC A61K31/05 A61K31/135 A61P7/02 A61P7/06 

Abstract RU 2347561 C2

FIELD: medicine; pharmacology.

SUBSTANCE: it is suggested to apply 2-methyl-6-isobornyl phenol, 4-methyl-2.6-diisobornyl phenol or 2-(dibutylamino)methyl-4-methyl-6-isobornyl phenol hydrochloride as agents with hemorheological, antiaggregant and antitrombogenic activity.

EFFECT: limitation of erythrocytes aggregation amplification in model of blood hyperviscosity, expressed antiaggregant activity in case of ADP-induced aggregation of platelets and reduction of thrombus mass compared to control in case of blood flow reduction in artery.

5 tbl, 25 ex

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RU 2 347 561 C2

Authors

Plotnikov Mark Borisovich

Krasnov Efim Avraamovich

Smol'Jakova Vera Ivanovna

Ivanov Ivan Sergeevich

Kuchin Aleksandr Vasil'Evich

Chukicheva Irina Jur'Evna

Buravlev Evgenij Vladimirovich

Dates

2009-02-27—Published

2007-04-23—Filed

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