DRUG WITH COMPLEX PHARMACOLOGICAL EFFECT FOR THE TREATMENT OF CARDIOVASCULAR DISEASES, CORRECTION OF CEREBRAL CIRCULATION DISORDERS, TREATMENT OF CONSEQUENCES OF CEREBROVASCULAR DISEASES (OPTIONS) Russian patent published in 2021 - IPC A61K31/05 A61P9/00 A61P25/00 A61P7/02 A61P39/06 

Abstract RU 2757874 C1

FIELD: pharmacology.

SUBSTANCE: invention relates to pharmacology and concerns the use of meso- and racemic forms of 2,6-di(1,7,7-trimethylbicyclo[2.2.1]heptane-exo-2-yl)-4-methylphenol as drugs for the treatment of cardiovascular diseases, correction of cerebral circulation disorders, treatment of consequences of cerebrovascular diseases. The meso-form is 2-{(1S, 2R, 4R)-1,7,7-trimethylbicyclo[2.2.1]heptane-2-yl}-6-{(1R, 2S, 4S)-1,7,7-trimethylbicyclo[2.2.1]heptane-2-yl}-4-methylphenol, the racemic form is 2,6-di{(1S,2R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptane-2-yl}-4-methylphenol and 2,6-di{(1R,2S,4S)-1,7,7-trimethylbicyclo[2.2.1]heptane-2-yl}-4-methylphenol.

EFFECT: technical result is expanding the arsenal of drugs for the treatment of cardiovascular diseases, correction of cerebral circulation disorders, treatment of consequences of cerebrovascular diseases, as well as enhancing pharmacological activity due to the stereospecific effect of isomers and due to the presence of a complex of pharmacological properties (antiradical, hemorheological, antiplatelet, antithrombogenic and neuroprotective activity, increase in cerebral blood flow), which also provides an increase in the effectiveness of treatment of the specified diseases.

2 cl, 7 tbl, 7 ex

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RU 2 757 874 C1

Authors

Plotnikov Mark Borisovich

Kuchin Aleksandr Vasilevich

Chernysheva Galina Anatolevna

Smolyakova Vera Ivanovna

Chukicheva Irina Yurevna

Dates

2021-10-22Published

2019-10-30Filed