METHOD OF ATHEROSCLEROSIS DIAGNOSTICS Russian patent published in 2009 - IPC A61B5/452 A61B5/02 

FIELD: medicine.

SUBSTANCE: monitoring of slow hemodynamic oscillations is accompanied with calculation of atherosclerosis localisation probability by formulas. In case of encephalopathy, y=-0.822-1.082463×10^-3(HR_P3)+2.108×10^-3(SV_M)-0.128(CO_M)+2.430×10^-2(EF_M)+2.297×10^-3(EF_P4), where HR_P3 is spectral intensity of heart rate variability within ultra-low frequency range; SV_M is average stroke volume; CO_M is average minute volume of circulating blood; EF_M is average ejection fraction in percentage; EF_P4 is intensity of ejection fraction variability within high-frequency range. In case of arterial hypertension: y=0.415+5.182×10^-4(HR_Power)-2.014×10^-3(HR_P2)-2.081×10^-3(HR_P3)-6.572×10^-2(CO_M)+4.323×10^-2(EF_S), where HR_Power is total spectral intensity of heart rate variability within 0-0.5 Hz; HR_P2 is spectral intensity of heart rate variability within very-low frequency range; HR_P3 is spectral intensity of heart rate variability within low-frequency range; CO_M is average minute volume of circulating blood; EF_S is ejection fraction dispersion during monitoring in percentage; in case of ischemic heart disease: y=0.436+4.678×10^-4(HR_Power)-8.509x10^-3(HR_P1)+4.972×10^-3(HR_P2)-1.515×10^-3(HR_P3)-5.741×10^-2(CO_M), where HR_Power is total spectral intensity of heart rate variability within 0-0.5 Hz; HR_P1 - spectral intensity of heart rate variability within ultra-low frequency range; HR_P2 is spectral intensity of heart rate variability within very-low frequency range; HR_P3 is spectral intensity of heart rate variability within low-frequency range; CO_M is average minute volume of circulating blood. Derived probabilities are used to evaluate localisation of atherosclerotic involvement.

EFFECT: possibility to optimise diagnostics associated with clinical oscillations of discirculatory encephalopathy, arterial hypertension and ischemic heart disease.

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