FIELD: medicine.
SUBSTANCE: invention relates to field of medicine, in particular to cardiology, neurology, ophthalmology, is used to carry out diagnostics of predisposition to ischemic neuroopticopathy in elderly people with ischemic heart disease (IHD), arterial hypertension (AH) and dyscirculatory encephalopathy (DEP). Blood is sampled from ulnar vein, blood samples are forms, from which DNS is separated, amplification of DNA fragments is pertformed, after that genotyping on polymorphisms del-425 and 3'-UTR of c-fms geneand polymorphism 64V of CCR2 gene is carried out, if in elderly women heterozygous genotype 64V/641 of polymorphism 64V of CCR2 gene, and heterozygous genotype 12 of polymorphism 3'-UTR of c-fms gene are detected, predisposition to ischemic neuroopticopathy is diagnosed.
EFFECT: detection of predisposition to ischemic neuroopticopathy in elderly people for administration of adequate preventive treatment.
7 tbl, 2 ex
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Authors
Dates
2010-12-10—Published
2009-09-15—Filed