FIELD: medicine.
SUBSTANCE: invention relates to field of medicine, namely to methods of laboratory diagnostics and concerns method of amyloidosis diagnostics in patients with Alzheimer's disease and set of means for carrying out diagnostics. Method lies in determining quantity of monomer β-amyloid, where in tested aliquot oligomer β-amyloid formations are first dissociated to monomers. If difference of quantity of β-amyloid monomers in tested and control aliquots is determined, conclusion about amyloidosis presence is made. Application of method and set of means ensures high sensibility and specificity of amyloidosis diagnostics in patients with Alzheimer's disease.
EFFECT: ensuring high sensibility and specificity of amyloidosis diagnostics in case of Alzheimer's disease.
11 cl, 1 dwg, 2 tbl, 2 ex
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Authors
Dates
2009-05-20—Published
2006-11-27—Filed