FIELD: biochemistry; medicine.
SUBSTANCE: invention relates to biochemistry and medicine and is a peptide of the H[isoD][pS]GYEVHH formula, where the serine residue is phosphorylated, and the aspartic acid residue is isomerized.
EFFECT: this peptide is capable of forming a stable zinc-mediated intermolecular complex with the metal-binding domain of human beta-amyloid and is used to treat Alzheimer's disease.
5 cl, 3 dwg, 3 ex
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PEPTIDE AND METHOD OF TREATMENT OF ALZHEIMER'S DISEASE | 2018 |
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AMMONIUM SALT OF HAEE PEPTIDE FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | 2022 |
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POTASSIUM SALT OF HAEE PEPTIDE FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | 2022 |
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EXOGENIC-INDUCED ANIMAL MODEL OF ALZHEIMER DISEASE | 2012 |
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Authors
Dates
2019-02-05—Published
2018-04-17—Filed