FIELD: medicine.
SUBSTANCE: invention refers to medicine and veterinary science. The method involves ultrasonic machining of virus-containing suspensions of various, including avid, tick-borne encephalitis virus strains. The ultrasonic machining is characterised with frequency 22 kHz, duration 1 min and performed three times every two min with an apparatus UZDN-1 or UZDN-A. Method allows improving diagnostic effectiveness of the prepared preparation manifested in increased titres detected in bloods serum of infected antibodies, diagnostic increases of antibody titres in hemagglutination inhibition reaction and reliability of confirmation rate of clinical diagnosis "tick-borne encephalitis" to 33%.
EFFECT: invention can be used in making diagnostic preparations and in improving clinical effectiveness of serum diagnostics of tick-borne encephalitis.
2 cl, 4 tbl, 3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| SET FOR DIFFERENTIAL DIAGNOSIS OF OMSK HEMORRHAGIC FEVER AND TICK-BORNE ENCEPHALITIS | 1993 |
|
RU2061959C1 |
| STRAIN OF VERNAL ENCEPHALITIS (TICK-BORNE ENCEPHALITIS) FAMILIES FLAVIVIRIDAE, SORTS FLAVIVIRUS VIRUS, USED FOR PREPARATION OF DIAGNOSTIC PREPARATIONS | 2007 |
|
RU2352632C2 |
| STRAIN OF VIRUS OF VERNAL ENCEPHALITIS FOR MAKING DIAGNOSTIC PREPARATIONS | 0 |
|
SU1634711A1 |
| METHOD OF PREPARING ANTIBODIES FOR MITE ENCEPHALITIS VIRUS DIAGNOSTIC PREPARATION PRODUCTION | 1993 |
|
RU2063245C1 |
| DIFFERENTIAL DIAGNOSIS METHOD FOR DETECTING THE CASES OF OMSK HEMORRHAGIC FEVER AND RUSSIAN TICK- BORNE ENCEPHALITIS | 1997 |
|
RU2133964C1 |
| METHOD FOR ANTIGENIC DIFFERENTIATION BETWEEN RUSSIAN TICK-BORNE ENCEPHALITIS VIRUS STRAINS | 0 |
|
SU1735362A1 |
| STRAIN OF VIRUS OF TICK-BORNE ENCEPHALITIS NO 132 FOR PREPARATION OF HEMAGGLUTINATING INACTIVATED DIAGNOSTICUM | 0 |
|
SU1071633A1 |
| STRAIN OF VIRUS OF TICK-BORNE ENCEPHALITIS NO 139 FOR PREPARATION OF HEMAGGLUTINATING INACTIVATED DIAGNOSTICUM | 0 |
|
SU1071634A1 |
| METHOD OF PREPARING THE SOLUBLE ANTIGEN-BASE VACCINE FOR TICK-BORNE ENCEPHALITIS CONTROL | 1994 |
|
RU2084242C1 |
| METHOD FOR ISOLATING ARBOVIRUSES, TICK- BORNE ENCEPHALITIS, IN PATICULAR | 2001 |
|
RU2205652C1 |
