FIELD: medicine.
SUBSTANCE: invention concerns area of experimental medicine, namely to experimental hepathology and can be used for modeling of hepatic encephalopathy. For this purpose four-chloride carbon is used in a combination with liquid paraffin in the ratio 1:1. The admixture is administered unitary weekly within 4-6 weeks. The model of hepatic encephalopathy is considered to be reached in presence of the expressed dystrophic process in hepatocytes, in vascular system and bile ducts of hepatoportal tracts, and at time decrease of rats' runway up to 100 - 150 s on distance of 30 cm on the seventh-eighth combination of a conditional and unconditional stimulus.
EFFECT: adequate replication of the model.
3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF SYSTEMIC FIBROSIS MODELLING | 2008 |
|
RU2371778C1 |
| METHOD OF DIAGNOSING CHRONIC LIVER DISEASES CAUSED BY POLYVIRAL INFECTION | 2011 |
|
RU2496426C2 |
| METHOD FOR HEPATIC FIXATION AT NARCOTIZED ANIMAL'S LIFE PERIOD | 2004 |
|
RU2269110C2 |
| METHOD FOR MODELLING MIOCARDIUM DYSTROPHY | 2004 |
|
RU2256954C1 |
| METHOD FOR MODELING PYLOROSTENOSIS | 2006 |
|
RU2321075C1 |
| METHOD FOR DIAGNOSIS INTRAHEPATIC CHOLESTASIS AT POLYVIRAL HEPATITIS | 2008 |
|
RU2397711C2 |
| METHOD FOR DIFFERENTIAL DIAGNOSTICS OF CHRONIC HEPATITIS AND CIRRHOSIS AT HEPATOCEREBRAL DYSTROPHY | 2005 |
|
RU2287165C1 |
| DIFFERENTIAL DIAGNOSTIC TECHNIQUE FOR LIVER DISEASES OF VARIOUS AETIOLOGIES ACCOMPANIED WITH INTRAHEPATIC CHOLESTASIS | 2008 |
|
RU2386969C2 |
| DIFFERENTIAL DIAGNOSTIC TECHNIQUE FOR INTRAHEPATIC CHOLESTASIS | 2008 |
|
RU2386134C1 |
| METHOD FOR PREDICTION OF PROGRESSION OF HEPATIC FAILURE IN INTRAHEPATIC CHOLESTASIS | 2008 |
|
RU2372619C1 |
