METHOD FOR PREPARATION OF ANTIADHESIVE COMPONENT BASED ON LECTIN-BINDING STRUCTURES Russian patent published in 2009 - IPC C12N1/20 A61K31/715 

Abstract RU 2367686 C1

FIELD: chemistry.

SUBSTANCE: colonies of the strain Lactobacillus fermentum 90 TS-4 (21) (All-Russian collection of industrial microorganisms B-7573) selected on grounds of agglutination with 0.1% concanavaline solution in concentration not less than 1.75·10-3 on liquid media MPC-1 are incubated. The cells are separated by centrifugation and obtained cultural liquor supernatant is concentrated over the membrane UM-20 "Diaflo". Obtained supernatant is removed and target product is purified and separated by method of affinity chromatography on concanavaline A-sepharose.

EFFECT: obtaining of the substance with expressed modulating activity in relation of high-adhesive strains of yeast-like fungi Candida albicans and opportunistic microorganisms strains Escherichia coli.

6 cl, 1 dwg, 1 tbl

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RU 2 367 686 C1

Authors

Anokhina Irina Viktorovna

Dalin Mikhail Viktorovich

Ermolaev Andrej Vladimirovich

Kravtsov Ehduard Georgievich

Jashina Natalija Vjacheslavovna

Dates

2009-09-20Published

2008-03-31Filed