FIELD: pharmacology.
SUBSTANCE: there is produced synthetic derivative of phthalyl-glycyl-agginyl-piperidide peptide expressing anticoagulant activity estimated by inhibiting amidolytic thrombin activity in system in vitro and double prolongation of rats' blood plasma coagulation as compared with the control values in tests activated partial thromboplastin and thrombin time tests and having formula 1, including pharmaceutically acceptable salts.
EFFECT: new synthetic peptide derivative expressing anticoagulant activity.
1 dwg, 2 tbl, 4 ex
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Authors
Dates
2009-12-27—Published
2007-06-08—Filed