Show metadata Hide metadata

(19)

(11)

2 382 763

(13)

(51)

IPC

C07C69/90(2006-01-01)

A61K31/60(2006-01-01)

A61P29/00(2006-01-01)

A61P29/02(2006-01-01)

(21) (22)

Application

2008121146/04, 2008-05-26

(24)

Start date

2008-05-26

(22)

Actual filing date

2008-05-26

(45)

Published

2010-02-27

(72)

Inventor

Brel' Anatolij Kuz'MichSpasov Aleksandr AlekseevichLisina Svetlana ViktorovnaMazanova Ljudmila Stepanovna

(73)

Holder

Gosudarstvennoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Gosudarstvennyj Meditsinskij Universitet Federal'Noe Agentstvo Po Zdravookhraneniju I Sotsial'Nomu Razvitiju"

METHOD OF ENHANCING PROLONGED FEBRIFUGAL ACTION AND REDUCTION OF TOXICITY OF SALICYLATES Russian patent published in 2010 - IPC C07C69/90 A61K31/60 A61P29/00 A61P29/02

Abstract RU 2382763 C2

FIELD: medicine.

SUBSTANCE: invention relates to method of enhancing prolonged februfungal action, increase of februfungal activity and reduction of toxicity of salicylates by introduction in therapeutic dose as salicylate of allyl ether of acetylsalicylic acid. Introduction of allyl gragment into carboxyl group of acetylsalicylic acid molecule allows to enhance prolonged februfungal action and reduce toxicity of acetylsalicylic acid.

EFFECT: application of allyl ether of acetylsalicylic acid as antipyretic will allow to reduce therapeutic dose of acetylsalicylic acid and reduce risk of development of side effects connected with intake of salicylates.

1 ex, 2 tbl

Similar patents RU2382763C2

Title	Year	Author	Number
DIALKYL- β -(O-SALICYLOYL)ETHYLPHOSPHONATES HAVING ANTITHERMIC ACTIVITY	2009	Brel' Anatolij Kuz'Mich Lisina Svetlana Viktorovna Spasov Aleksandr Alekseevich Mazanova Ljudmila Stepanovna	RU2420532C1
COMPLEX OF PECTIN BIOPOLYMER AND ACETYLSALISYLIC ACID	2012	Minzanova Salima Takhijatullovna Vyshtakaljuk Aleksandra Borisovna Tsepaeva Ol'Ga Viktorovna Mironova Ljubov' Gennad'Evna Mironov Vladimir Fedorovich Zobov Vladimir Vasil'Evich	RU2503455C1
WATER-SOLUBLE SALAMIDE DERIVATIVE POSSESSING TRANQUILISING, NOOTROPIC AND ANALGESIC ACTIVITY	2012	Brel' Anatolij Kuz'Mich Petrov Vladimir Ivanovich Lisina Svetlana Viktorovna Kovalev Dmitrij Gennad'Evich Salomatina Julija Nikolaevna Mjagkova Irina Alekseevna	RU2540464C2
AGENT POSSESSING ANTIAGGREGANT, CYTOPROTECTIVE AND ANTIOXIDANT ACTIVITY	2018	Tanashyan Marine Movsesovna Fedorova Tatyana Nikolaevna Stvolinskij Sergej Lejbovich Andreeva Lyudmila Aleksandrovna Nagaev Igor Yulianovich Migulin Vasilij Andreevich Shabalina Alla Anatolevna Trubitsyna Irina Evgenevna Lopachev Aleksandr Vasilevich Kulikova Olga Igorevna Abaimov Denis Aleksandrovich	RU2694061C1
POLYMERIC WATER-SOLUBLE ANALOG OF ACETYL-SALICYLIC ACID AND METHOD OF ITS SYNTHESIS	2000	Nikolaevskij V.A. Slivkin A.I. Arzamastsev A.P. Lapenko V.L. Shchekina I.A. Iskra L.I. Gus'Kova T.A.	RU2201234C2
COMPLEX COMPOUND EXHIBITING ANTIFLAMMATORY AND ANTIULCEROUS ACTIVITY	0	Baltina L.A. Davydova V.A. Tolstikova T.G. Sharipova F.V. Murinov Yu.I. Zarudij F.S. Lazareva D.N. Tolstikov G.A. Bondarev A.I.	SU1566700A1
METHOD OF LIVER PROTECTION FROM XENOBIOTICS IN EXPERIMENT	2000	Shchekina I.A. Gladkov B.A. Nikolaevskij V.A. Lobeeva N.V. Mednikova G.N.	RU2195936C2
RIFAMPICIN-BASED MEDICATION WITH PROLONGED ACTION FOR TREATMENT OF RESISTENT FORMS OF TUBERCULOSIS	2010	Severin Evgenij Sergeevich Erokhin Vladislav Vsevolodovich Demikhova Ol'Ga Vladimirovna Barsegjan Gevorkbek Gajkovich Zykova Irina Evgen'Evna Bocharova Irina Vladimirovna Vorontsov Evgenij Alekseevich Kuznetsov Sergej Leonidovich Severin Sergej Evgen'Evich	RU2418585C1
METHOD FOR SALICYLATES QUANTIFICATION IN BLOOD PLASMA	2016	Abaimov Denis Aleksandrovich Sariev Abrek Kuangalievich Tanashyan Marine Movsesovna Shabalina Alla Anatolevna Telenkova Nadezhda Grigorevna Spavronskaya Larisa Rafailovna	RU2622996C1
METHYL 6-ACETYL-7-(2,5-DIMETOXYPHENYL)-4,7-DIHYDROTETRASOLO[1,5-a]PYRIMIDINE-5-CARBOXYLATE, DEMONSTRATING ANTI-FEVER ACTIVITY	2009	Gejn Vladimir Leonidovich Panova Ol'Ga Sergeevna Syropjatov Boris Jakovlevich Kovaleva Marina Jur'Evna	RU2413730C1

RU 2 382 763 C2

Authors

Brel' Anatolij Kuz'Mich

Spasov Aleksandr Alekseevich

Lisina Svetlana Viktorovna

Mazanova Ljudmila Stepanovna

Dates

2010-02-27—Published

2008-05-26—Filed