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2 391 668

(13)

(51)

IPC

G01N33/53(2006-01-01)

(21) (22)

Application

2009119940/15, 2009-05-26

(24)

Start date

2009-05-26

(22)

Actual filing date

2009-05-26

(45)

Published

2010-06-10

(72)

Inventor

Lutsenko Mikhail TimofeevichAndrievskaja Irina Anatol'Evna

(73)

Holder

Uchrezhdenie Rossijskoj Akademii Meditsinskikh Nauk Dal'Nevostochnyj Nauchnyj Tsentr Fiziologii I Patologii Dykhanija Sibirskogo Otdelenija Ramn

METHOD OF EVALUATING CASPASE-3 ACTIVITY IN PLACENTA IN PREGNANCY COMPLICATED BY HERPES-VIRAL INFECTION Russian patent published in 2010 - IPC G01N33/53

Abstract RU 2391668 C1

FIELD: medicine.

SUBSTANCE: method lies in determining caspase-3 and titre of antibodies to herpes virus by EIA method in placenta. If titre of antibodies to herpes virus is 1:12800 and content of caspase-3 is 103.7±0.8 ng/ml conclusion about increased risk of damaging action of caspase-3 on syncytiotrophoblast of placenta is made.

EFFECT: method has high sensitivity and allows to predict morphofunctional damage of syncytiotrophoblast of placenta in case of exacerbation of herpes-viral infection during pregnancy.

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RU 2 391 668 C1

Authors

Lutsenko Mikhail Timofeevich

Andrievskaja Irina Anatol'Evna

Dates

2010-06-10—Published

2009-05-26—Filed