METHOD OF OPTIMISING FUNCTIONAL REACTIVITY OF CARDIO-VASCULAR SYSTEM IN CASE OF CRISIS COURSE OF ARTERIAL HYPERTENSION WITH DISTURBANCE OF GLUCOSE TOLERANCE Russian patent published in 2010 - IPC A61K31/216 A61K31/4155 A61P9/12 

Abstract RU 2394564 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to cardiology, and deals with normalisation of functional reactivity of cardio-vascular system (CVS) in case of crisis course of arterial hypertension with disturbance of glucose tolerance. For this purpose estimation of CVS functional reactivity state under psychoemotional load is carried out by registration of systolic diastolic everage dynamic pressure (APav.dyn.) and heart rate (HR). On the basis of obtained data functional reactivity index (FRI) is determined before and after load, using the formula: FRI= APav.dyn.x HR)100 (conv. units). If FRI value after load increases on more than 20 conv.units, treatment including irbersartan 150 mg in the morning 1 time and lacidipine 4 mg in the morning 1 time during not less than 2 months.

EFFECT: such complex of medicamentary therapy in combination with empirically selected treatment duration ensures normalisation of CVS functional reactivity in said group of patients due to potentiation of therapeutic effect of applied medications.

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RU 2 394 564 C1

Authors

Medvedev Il'Ja Nikolaevich

Krasnova Evgenija Gennad'Evna

Zavalishina Svetlana Jur'Evna

Bespartochnyj Boris Dmitrievich

Dates

2010-07-20Published

2009-04-13Filed