PHARMACEUTICAL PREPARATION OF ABSORPTION TYPE FOR THRANSCUTANEOUS INTRODUCTION Russian patent published in 2010 - IPC A61K9/70 A61K31/137 A61P25/16 A61L15/58 A61F13/02 

FIELD: medicine.

SUBSTANCE: described is stable pharmaceutical preparation of absorption type for transcutaneous introduction, which includes bottom layer and adhesive layer, containing metal chloride, adhesive and at least one composition from (-)-(R)-N, α-dimethyl-N-2-propinylphenethylamine and its hydrochloride, where adhesive layer is subjected to crosslinking.

EFFECT: pharmaceutical preparation of absorption type for transcutaneous introduction of selegiline or selegiline hydrochloride does not suffer reduction of cohesive strength of adhesive layer even in presence of sweat components caused by excretion of sweat during wearing, and is free of cohesive destruction and remains of adhesive when preparation is removed.

4 cl, 2 tbl, 22 ex