FIELD: chemistry.
SUBSTANCE: invention relates to a method for synthesis of a novel acetylene derivative of betulin - 3β,28-di-O-acetyl-29-nor-20(30)-lupine from triterpenoid derivatives of the lupane type, having diverse biological activity. The method involves reaction of 3β,28-diacetyl-20-keto-29-norlupane with phosphoryl chloride in a medium of pyridine while boiling. Output is equal to 73%.
EFFECT: high yield.
1 cl, 1 ex
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