IMIDAZOPYRAZINES AS TYROSINE KINASE INHIBITORS Russian patent published in 2010 - IPC C07D487/04 A61K31/4985 A61K31/55 A61P1/04 A61P7/06 A61P13/12 A61P17/00 A61P27/06 A61P33/02 A61P37/06 A61P9/00 A61K31/535 A61P29/00 A61P3/10 A61P11/06 A61P15/08 A61P25/00 A61P31/12 A61P35/02 A61P43/00 A61P19/00 

Abstract RU 2405784 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: present invention refers to new imidazopyrazines of formula where Q1 and R1 have the values specified in the patent claim, and to their pharmaceutically acceptable salts showing IGF-1R enzyme inhibiting activity and applicable for treatment and/or prevention of various diseases and conditions which are sensitive to tyrosine kinase inhibition.

EFFECT: preparation of the compounds showing IGF-1R enzyme inhibiting activity.

27 cl, 294 ex

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RU 2 405 784 C2

Authors

Bek Patrisija Ehnn

Sesario Kara

Koks Mehtt'Ju

Dun Khan'-Tsin

Forman Kennet

Malvikhill Mark Dzhozef

Najgro Ehntoni Innochentso

Saroglou Lidija

Shtajnig Arno G.

Sun' Inchuan'

Vehn Tsinkhua

Verner Duglas

Uilkes Robin

Uill'Jams Dzhonatan

Dates

2010-12-10Published

2004-10-14Filed