IMIDAZOPYRAZINES Russian patent published in 2016 - IPC C07D487/04 A61K31/4985 A61K31/506 A61K31/5377 A61P35/02

Abstract RU 2600327 C2

FIELD: pharmaceutics.

SUBSTANCE: invention relates to novel compounds of formula I and pharmaceutically acceptable salts thereof, in which values for groups R¹, R², R³, R⁴ and X are defined in patent claim. Invention also relates to pharmaceutical compositions, having activity of inhibitor of Fms-like tyrosine 3 (FLT3) containing said compounds and pharmaceutically acceptable salts thereof.

EFFECT: invention relates to use of said compounds and pharmaceutical compositions for treating, controlling or relieving symptoms of AML (acute myeloid leukaemia).

35 cl, 93 ex, 1 tbl

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RU 2 600 327 C2

Authors

Lyuk Kin-Chun Tomas

Sot Majkl

Dates

2016-10-20—Published

2012-03-14—Filed